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steroids cause blood sugar to rise

Dr. Gregory Hill
Dr. Gregory Hill

Board-Certified Geriatrician

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Medically Reviewed

You're on steroids for your chronic pain, and your blood sugar monitor is flashing red. Again. You've been checking it every morning for weeks, and it's never been this high. You're not diabetic, so what the heck is happening? This isn't some random fluctuation—it's steroids cause blood sugar to rise, and it's hitting you hard.

Let's be real: when your doctor prescribes steroids for that terrible flare-up of lupus or rheumatoid arthritis, they don't hand you a warning label that says "This will turn your blood sugar into a rollercoaster." They talk about the benefits, the quick relief, the life-changing difference. What they don't tell you is how steroids cause blood sugar to rise to dangerous levels. And honestly? That's not just a side effect—it's a full-blown emergency waiting to happen for millions of people. I've seen it happen to friends, family, and patients in my own medical circle. It's not a rare thing. It's the silent crisis hiding behind every steroid prescription.

The Uncomfortable Truth About Steroids and Blood Sugar

Here's the raw reality: when you take steroids, whether it's prednisone for asthma, dexamethasone for cancer treatment, or even those over-the-counter topical steroids for skin rashes, your body doesn't just tolerate them. It starts to rebel against normal blood sugar regulation. Steroids cause blood sugar to rise because they directly interfere with how insulin works. Insulin is the hormone that tells your cells to absorb glucose from your blood. Steroids make your body resist insulin, so glucose just piles up in your bloodstream. It's not a slow process—it can happen within days of starting treatment. And for people with undiagnosed prediabetes? It's a direct path to a diabetic emergency.

I've talked to countless people who started steroids for a knee injury, got a quick fix, and then had to be rushed to the ER because their blood sugar was over 400. They didn't have any symptoms of diabetes before—just a sudden spike. That's steroids cause blood sugar to rise in action. It's not "maybe" or "sometimes." It's a guaranteed physiological response. The body doesn't care if you're on steroids for a good reason. It just reacts. And that reaction is dangerous.

Think about it: steroids mimic cortisol, the stress hormone. When you're stressed, your body naturally raises blood sugar to give you energy for a fight-or-flight response. Steroids do the same thing, but they do it constantly. Your body thinks it's under constant stress, so it keeps pumping out glucose. And since steroids cause blood sugar to rise, your insulin can't keep up. It's a perfect storm. You're not just getting a temporary high—your body is stuck in overdrive, and it's not going to slow down until you stop taking the steroids.

Let me be blunt: this isn't something you can ignore. I've seen people dismiss their rising blood sugar as "just a temporary thing" while they're on steroids. Then they get a diabetic coma because they didn't get checked. Steroids cause blood sugar to rise, and ignoring it is like ignoring a fire alarm. It's not a minor detail—it's a life-threatening side effect that needs immediate attention.

Why Steroids and Blood Sugar Don't Mix: The Science You Actually Need to Know

Okay, let's cut through the medical jargon. Steroids cause blood sugar to rise because they disrupt two key processes in your body: insulin sensitivity and glucose production. When you take steroids, they make your liver produce more glucose, and they make your muscles and fat cells less responsive to insulin. So you're getting more sugar from your liver, and your body can't use it properly. It's like pouring gasoline on a fire while the fire alarm is broken.

Here's what happens in real time: after you take a steroid dose, your blood sugar starts climbing within hours. By the next morning, it's often significantly higher than normal. For people on long-term steroid therapy—like those with autoimmune diseases—this isn't a one-time thing. It's a daily battle. Your blood sugar might be fine on days you skip the dose, but it spikes the next day. It's not a coincidence. Steroids cause blood sugar to rise consistently, no matter how small the dose.

And here's the kicker: the higher the dose, the worse it gets. A 5mg prednisone pill might raise your blood sugar by 50 points. A 20mg dose? It can jump 100 points or more. But even low doses—like those used for allergies or skin conditions—can cause problems. I've had patients tell me they were on a "low dose" steroid cream for eczema, and their blood sugar went through the roof. Steroids cause blood sugar to rise, and it doesn't care about the size of the dose.

Now, let's talk about who's most at risk. If you have a family history of diabetes, or if you're overweight, steroids will hit you harder. But even if you're healthy, steroids cause blood sugar to rise. It's a direct physiological effect. Your body doesn't get a pass because you're young or fit. The science doesn't care about your age or your weight. It just happens. And the longer you're on steroids, the more your body gets used to the disruption. It's not like your blood sugar returns to normal immediately after you stop taking steroids. It can take weeks or months for your insulin sensitivity to recover. During that time, you're still at risk for high blood sugar episodes.

Let's be clear: this isn't just about numbers on a monitor. High blood sugar from steroids can lead to serious complications like nerve damage, kidney problems, and heart disease. It's not a temporary thing you can just "get over." Steroids cause blood sugar to rise, and if you don't manage it, you're setting yourself up for long-term health issues. I've seen people who thought they were fine after stopping steroids, only to be diagnosed with type 2 diabetes years later. The damage was already done.

Why Your Doctor Might Not Be Talking About This (And It's Not Your Fault)

Here's the uncomfortable truth: your doctor isn't ignoring steroids cause blood sugar to rise. They're just not trained to talk about it in the way you need to hear it. Most doctors focus on the immediate benefits of steroids—like reducing inflammation or pain. They tell you, "This will help your condition," and they don't say, "But it might send your blood sugar through the roof." Why? Because it's not their primary focus. They're thinking about your arthritis flare-up, not your blood sugar numbers.

And let's be real: the medical system is broken. Doctors are rushed, they're dealing with 20-minute appointments, and they're not getting enough training on how steroids affect blood sugar. I've talked to doctors who admit they don't know the full extent of how steroids cause blood sugar to rise. They know the basics, but they don't know how to manage it day-to-day. So they might say, "Check your blood sugar," but they don't explain what to do if it's high. They don't give you a plan for when your blood sugar spikes because of steroids.

But here's the thing: it's not your doctor's fault. It's the system. And it's not your fault for not knowing. Most people don't realize steroids cause blood sugar to rise until it's too late. You're not supposed to know this. It's not common knowledge. It's not something you learn in a health class. You're supposed to trust your doctor, and they're supposed to tell you the risks. But they don't always do that. So when your blood sugar is rising, you feel alone, confused, and scared. And that's exactly what happens to millions of people every year.

I've had patients tell me they felt embarrassed to ask about blood sugar when they were on steroids. They thought, "This is just a side effect, I shouldn't worry." But steroids cause blood sugar to rise, and it's not something you should ignore. It's not "just a side effect." It's a major health risk that needs attention. And the fact that your doctor didn't mention it doesn't mean it's not serious. It just means they're not trained to handle it properly. That's not your problem to solve.

So what do you do? You have to become your own advocate. You can't rely on your doctor to tell you everything about steroids cause blood sugar to rise. You have to ask the questions yourself. You need to know your blood sugar numbers. You need to know what to do if they're high. And you need to know that steroids cause blood sugar to rise is a real, immediate risk—not something that might happen, but something that will happen if you're not careful.

Managing Blood Sugar When You're on Steroids: What Actually Works

Okay, let's get practical. If you're on steroids, you need a plan. You can't just hope your blood sugar will stay normal. Steroids cause blood sugar to rise, so you have to work with it, not against it. First, talk to your doctor about getting your blood sugar checked regularly. Not just once, but every week. Get a home glucose monitor if you don't have one. It's not a luxury—it's a necessity. You need to know what's happening, especially since steroids cause blood sugar to rise so quickly.

Here's what I've found works: adjust your diet. You don't need to go on a strict diet, but you should avoid sugary foods and refined carbs. Sugar is the last thing you want when steroids cause blood sugar to rise. Instead, focus on lean proteins, vegetables, and whole grains. And don't skip meals. Skipping meals can make your blood sugar drop too low, which is dangerous when you're already dealing with high blood sugar from steroids. It's a balancing act, but it's doable.

Exercise is another key part of managing blood sugar when you're on steroids. But not intense exercise—start with short walks after meals. Walking helps your body use glucose more effectively, which can counteract the effects of steroids. I've seen patients who started walking 20 minutes a day after meals see their blood sugar stabilize. It's not a cure, but it's a powerful tool. And it's free, so why not try it?

Now, let's talk about medication. If your blood sugar stays high despite diet and exercise, you might need to talk to your doctor about temporary diabetes medication. It's not a permanent solution, but it's a short-term fix to keep your blood sugar in check while you're on steroids. Don't wait until it's an emergency. If steroids cause blood sugar to rise, get help before it gets out of hand. I've had patients who waited too long and ended up in the hospital because they didn't get help sooner.

And remember: steroids cause blood sugar to rise, but it's not permanent. Once you stop taking steroids, your blood sugar will gradually return to normal. How long it takes depends on how long you were on them and your overall health. But while you're on them, you have to manage it. Don't think, "I'll just deal with it later." That's how people end up with long-term health problems. Manage it now, because steroids cause blood sugar to rise is a real, immediate threat.

I know it's frustrating. You're on steroids for a reason—you need them. But you also need to protect your blood sugar. It's not about being perfect. It's about being aware. Steroids cause blood sugar to rise, so you have to be ready for it. Check your blood sugar daily. Eat smart. Move your body. And don't be afraid to ask your doctor for help. They're there to help you, even if they didn't tell you about this risk upfront. It's not their fault, but it is your responsibility to take care of yourself.

So next time you're prescribed steroids, ask your doctor: "Will this cause my blood sugar to rise?" Don't wait for the high blood sugar to happen. Be proactive. Steroids cause blood sugar to rise, and knowing that is the first step to staying healthy. It's not a minor detail—it's a critical piece of information that could save your health. And if your doctor doesn't talk about it, ask again. And again. Because steroids cause blood sugar to rise isn't something you can ignore. It's something you need to manage every single day you're on those medications.

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Dr. Sarah Mitchell

Dr. Gregory Hill

Verified Expert

Board-Certified Geriatrician | Health Director at Health

Dr. Hill has spent 20 years dedicated to improving the health and quality of life of older adults through comprehensive geriatric assessment.

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